Identification of potential neuromodulatory targets of stigmasterol through reverse docking integrated network pharmacology approach
نویسندگان
چکیده
منابع مشابه
Using reverse docking to identify potential targets for ginsenosides
BACKGROUND Ginsenosides are the main ingredients of ginseng, which, in traditional Eastern medicine, has been claimed to have therapeutic values for many diseases. In order to verify the effects of ginseng that have been empirically observed, we utilized the reverse docking method to screen for target proteins that are linked to specific diseases. METHODS We constructed a target protein datab...
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پژوهش حاضر ارائه ی توصیفی است از نظام آوایی گویش لری شهر اندیمشک، واقع در شمال غربی استان خوزستان. چهارچوب نظری این پژوهش، انگاره ی پسازایشی جزءمستقل می باشد. این پایان نامه شامل موارد زیر است: -توصیف آواهای این گویش به صورت آواشناسی سنتی و در قالب مختصه های زایشی ممیز، همراه با آوانوشته ی تفصیلی؛ -توصیف نظام آوایی گویش لری و قواعد واجی آن در چهارچوب انگاره ی پسازایشی جزءمستقل و معرفی برهم کن...
Identification of Agents with Potential Leishmania Malate Dehydrogenase Inhibitor Activity: A Proteomic and Molecular Docking Approach
Background and purpose: Leishmaniasis is one of the most important infectious diseases caused by different species of the Leishmania, which is a public health problem worldwide. So far, no effective vaccine is introduced for this disease and drug therapy is associated with many side effects. Therefore, this study was designed to identify novel FDA-approved compounds with anti-leishmanial activ...
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in fact, this study focused on the following questions: 1. is there any difference between the effect of functional/notional approach and the structural approaches to language teaching on the proficiency test of efl learners? 2. can a rather innovative language test referred to as "functional test" ge devised so so to measure the proficiency test of efl learners, and thus be as much reliable an...
15 صفحه اولReverse Docking Study Unravels the Potential Mycobacterium tuberculosis Enzyme Targets of Agelasine F
The natural product Agelasine F found in marine sponge Agelas sp. along with the known inhibitors of the target enzymes in Mycobacterium tuberculosis (Mtb), and the first-line tuberculosis (TB) drugs have been docked to enoyl reductase (InhA), Isoniazid-resistant I21V and S94A enoylACP (COA) reductase mutant enzymes, 7,8-diaminopelargonic acid synthase (DAPAS), pantothenate synthetase (PS), and...
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ژورنال
عنوان ژورنال: IBRO Reports
سال: 2019
ISSN: 2451-8301
DOI: 10.1016/j.ibror.2019.07.1673